Salt-bridge networks within globular and disordered proteins: characterizing trends for designable interactions
نویسندگان
چکیده
منابع مشابه
Salt-bridge networks within globular and disordered proteins: characterizing trends for designable interactions.
There has been considerable debate about the contribution of salt bridges to the stabilization of protein folds, in spite of their participation in crucial protein functions. Salt bridges appear to contribute to the activity-stability trade-off within proteins by bringing high-entropy charged amino acids into close contacts during the course of their functions. The current study analyzes the mo...
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ژورنال
عنوان ژورنال: Journal of Molecular Modeling
سال: 2017
ISSN: 1610-2940,0948-5023
DOI: 10.1007/s00894-017-3376-y